Acute myocardial infarction.
Conditions
Interventions
1. Percutaneous Coronary Intervention
2. Intravascular Ultrasound
3. Fractional Flow Reserve.
Sponsors
Leiden University Medical Center
Department of Cardiology
Albinusdreef 2
2300 RC Leiden
Eligibility
Inclusion criteria
Inclusion criteria: 1. Between 18 and 80 years of age; 2. ECG evidence of an acute myocardial infarction; 3. De novo native culprit lesion; 4. Target vessel with a reference diameter between 2.25 and 3.75 mm; 5. Target lesion lenth <=24 mm; 6. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Rescue PTCA; 2. Start symptoms >9 hours before the procedure; 3. Left main lesion with >=50% diameter stenosis; 4. Triple vessel disease; 5. Involvment of a major side branch; 6. Previous PCI or CABG of the culprit vessel; 7. Renal insufficiency; 8. Unwilling or unable to comply with the study requirements or follow-up evaluations; 9. Contraindication for abciximab; 10. Extensive peripheral vascular disease; 11. Non-cardiac illness with a life expectancy less than 12 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In-lesion late loss at 9 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. MACE (death, myocard infarction, target vessel revascularisation, target lesion revascularisation) at 12 months; 2. Incomplete stent apposition at 9 months; 3. Minimal lumen areat at 9 months; 4. Fractional flow reserve at 9 months. | — |
Contacts
Public ContactM.J. Schalij
Leiden University Medical Center (LUMC), Department of Cardiology, P.O. Box 9600
Outcome results
None listed