Chronic Limb Threatening Ischemia (CLTI)
Conditions
Interventions
Prehabilitation program. Participants will be screened by a nurse practitioner, physiotherapist and dietician. In case of criteria for frailty (as described in ‘appendix’), a geriatrician will perform
Sponsors
Prof. dr. L. van der Laan
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Aged 65 years or older - All genders - All ethnicities - Diagnosis of CLTI (Chronic Limb Threatening Ischemia), based on either: o Anamnestic complaints of ischemic rest pain or night pain o (Minor) tissue loss, non-healing ulcer and/or focal gangrene with diffuse pedal ischemia[11] o Impaired perfusion, quantified by a flat or barely pulsatile ankle or metatarsal PVR (pulse volume recording), a low resting ankle pressure, a low ankle brachial index and/or a low toe pressure. - Indication and informed consent to undergo either endovascular or surgical treatment - No need to start treatment earlier then 3 weeks, counting from the moment of diagnosis
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Dementia according to DSM-V - Inability to complete questionnaires, due to either lingual or cognitive incompetence. - Need for urgent surgery (<3 weeks)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will be in-hospital mortality, 30 day, 6 month and 12 month mortality, complications, rates of major amputations, amputation free survival (AFS), length of hospital stay, Quality of Life (QoL, measured by using the WHOQOL-BREF, SF-12 and VascuQoL-6-NL), functional outcome, cognitive function and biochemistry. | — |
Contacts
Public ContactAnne Meulenbroek
Amphia Ziekenhuis
Outcome results
None listed