Light products, anticipatory and consummatory reward, taste activation (brain activation). Light producten, verwachting van een beloning, consumptie van een beloning, smaak activatie (brein activatie).
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: 18-35 years; 2. Being female; 3. BMI: 18.5 – 25.0 kg/m2; 4. Healthy (as judged by the participant); 5. Being right handed; 6. Willing to comply with the study procedures; 7. Willing to be informed about incidental findings of pathology; 8. Having given written informed consent; 9. Successful completion of the training session.
Exclusion criteria
Exclusion criteria: 1. Restraint eating (women: score > 2.80) 2. Lack of appetite 3. Having difficulties with swallowing/eating 4. Usage of an energy restricted diet during the last two months 5. Weight loss or weight gain of 5 kg or more during the last two months 6. Stomach or bowel diseases 7. Diabetes, thyroid disease, kidney disease and other endocrine disorders 8. Having a history of neurological disorders 9. Having taste or smell disorders 10. Having schizophrenia or another serious mental illnesses 11. Usage of daily medication other than oral contraceptives, Paracetamol or hay fever tablets 12. Pregnancy during the last 6 months, having the intention to become pregnant or lactating 13. Smoking on average more than one cigarette/cigar a day 14. Being allergic/intolerant for products under study 15. Exclusive consumption of ‘light’ versions of beverages 16. Avoidance of ‘light’ versions of beverages 17. Disliking the beverages under study 18. Working or doing an internship/thesis at the group Sensory science and eating behavior (WUR) 19. Current participation in other nutrition related or medical research 20. Having a history of or current alcohol consumption of on average more than 28 units per week 21. Having a contra-indication to MRI scanning (including, but not limited to): Claustrophobia Epilepsy Pacemakers and defibrillators Intraorbital or intraocular metallic fragments Ferromagnetic implants Presence of non-removable metal objects in the mouth
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The 1st secondary study parameter/endpoint is the correlation between brain activation in response to exposure to an anticipatory or a consummatory reward and reaction times and errors (push/pull measure). In addition, two groups will be made based on the product choice outcome and anticipatory reward responses and consummatory reward responses are compared between those groups (i.e. there is looked at the group*reward response interaction). The 2nd secondary study parameter/endpoint is the correlation between brain activation in response to exposure to an anticipatory or a consummatory reward and subject characteristics like reward sensitivity, delayed discounting, impulsivity, health attitude, stress, executive functioning and food neophobia. | — |
Primary
| Measure | Time frame |
|---|---|
| The main study parameters/endpoints are (1) the difference in brain activation between an anticipatory reward and a consummatory reward and (2) the difference in brain activation between a consummatory reward labeled as light versus labeled as regular. | — |
Contacts
Bomenweg 2