Juvenile Dermatomyositis.
Conditions
Interventions
Treadmill training and strength training, minimal twice a week at home (30-60 minutes per session), for 12 weeks. The control group also enters the training arm directly after completing the initial p
Sponsors
University Medical Center Utrecht (UMCU), Wilhelmina Children’s Hospital (WKZ), Child Development and Exercise Center.
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosed Juvenile Dermatomyositis by a pediatric rheumatologist using the Bohan and Peter criteria; 2. Be able to follow instructions regarding testing and training; 3. Parental and child informed consent; 4. Age between 8-18 years of age.
Exclusion criteria
Exclusion criteria: 1. Insufficient understanding of the Dutch language in both children and parents; 2. Medical events that might intervene with the outcome of testing; 3. Medical status that will not allow maximal exercise testing (e.g. acute fever, heart conditions).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Exercise capacity during a graded exercise test with respiratory gas analysis; 2. Muscle strength as assessed with hand-held dynamometry; 3. Fatigue as assessed with the PEDSQL fatigue scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Muscle soreness as assessed with the 10 cm Visual Analogue Scale; 2. Muscle function as assessed with the Childhood Myositis Assessment Scale (CMAS); 3. Walking distance at the 6-minutes walking test; 4. Quality of life as assessed with the PEDSQL questionnaire; 5. Functional ability as assessed with the Childhood Health Assessment Questionnaire; 6. Physical activity as assessed by 7 days activity monitoring using an Actical accelerometer; 7. Physical activity enjoyment as assessed with the Physical Activity Enjoyment Scale. | — |
Contacts
Public ContactM. Brussel, van
Child Development and Exercise Center Wilhelmina’s Children’s Hospital/UMCU KB. 02.056.0, Lundlaan 6
Outcome results
None listed