FoBoMin preterm infants bone mineralization length
Conditions
Interventions
- Questionnaire
- Anthropometric measurements
- Quantitative ultrasound
- DEXA-scan
Sponsors
Radboud University Medical Centre
Eligibility
Inclusion criteria
Inclusion criteria: The children who were included in a former cohort study were born during the year 2004 (68 children with the old composition of parenteral feeding) and 2005 (79 children with the new composition of parenteral feeding). They had at birth a gestational aged below 34 weeks, were admitted to our NICU of the first day of life and had an expected duration of parenteral nutrition of more than five days. Of these former cohorts 55 respectively 60 children were seen at the follow-up at two years and these children we have invited for the current FoBoMin study.
Exclusion criteria
Exclusion criteria: - Asphyxia - Congenital malformation - Renal or hepatic insufficiency at birth - No follow up at 2 years of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine whether increased calcium and phosphate intake (2005 group) resulted in improved Bone mineral content (BMC) and Bone mineral density (BMD) compared to the group with less calcium and phosphate intake (2004 group) at the age of 8-10 years, determined by DEXA-scan. | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine whether increased perinatal calcium and phosphate intake (group 2005) compared to lower perinatal calcium and phosphate intake (group 2004) at the age of 8-10 years results in: - improved BTT (bone-transit time= speed of sound (m/sec)) determined with QUS. - improved length, weight, head circumference | — |
Contacts
Public ContactM.E. Putten, van der
Radboud UMC Postbus 9101
Outcome results
None listed