acute left-sided malignant colonic obstruction
Conditions
Interventions
Patients will be randomized to either emergency surgery (current standard treatment) or colonic stenting as bridge to elective surgery.
Sponsors
P. Fockens, MD, PhD,
professor of Endoscopy
Academic Medical Center
Dept. of gastroenterology, C2
PO Box 22700
1100 DE Amsterdam
the Netherlands
tel: 0031 (0)20 5663534
fax: 0031 (0)20 6917033
e-mail: p.fockens@amc.nl
Eligibility
Inclusion criteria
Inclusion criteria: 1. Symptoms of left-sided (colon descendens, sigmoid or rectum) malignant colonic obstruction existing less than one week defined as obstructive symptoms with dilation of the colon on either plain abdominal X-ray and typical abnormalities on a gastrografin enema study or CT-abdomen with contrast, compatible with a malignant colonic stricture; 2. Age > 18 years; 3. Informed consent.
Exclusion criteria
Exclusion criteria: 1. Peritonitis, perforation, fever, sepsis or other serious complications demanding urgent surgery; 2. ASA IV or V; 3. Obstruction due to non-colonic malignancies or from a benign origin; 4. Distal tumor margin less than 10 cm from the anal verge.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness of both strategies in terms of quality of life, morbidity and mortality. | — |
Secondary
| Measure | Time frame |
|---|---|
| Costs of both strategies. | — |
Contacts
Public ContactIlja Peute
Academic Medical Center (AMC), Department of gastroenterology, C2, P.O. Box 22760
Outcome results
None listed