acute myocardial infarction, scheduled for emergency coronary angioplasty
Conditions
Interventions
Percutane Coronaire Interventie.
Sponsors
Dr Harry Suryapranata
Dr Giuseppe De Luca
Department of Cardiology
ISALA Klinieken
Hospital De Weezenlanden
Zwolle, The Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with acute myocardial infarction, presenting within 6 hours after symptom-onset, or those presenting between 6 and 24 hours if persisting chest pain associated with clinical evidence of on-going ischemia occurs; 2. Culprit lesion in a native coronary artery, suitable for stenting; 3. Lesion length of 2.5 mm; 4. Able to deliver the stent to target lesion (absence of diffuse disease or excessive proximal vessel tortuosity); 5. Absence of no-reflow or extensive thrombus throughout vessel.
Exclusion criteria
Exclusion criteria: 1. Women of child-bearing potential; 2. Severe hepatic or renal disease; 3. Previous participation in the study; 4. Life expectancy of < 1 year; 5. Factors making follow-up difficult; 6. Acute myocardial infarction pre-treated with thrombolysis; 7. Unprotected left main disease or single remaining vessel; 8. Target lesion in a bifurcation with a large side-branch; 9. Known sensitivity to aspirin or coumarin; 10. Unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major adverse cardiac clinical events (death, re-infarction, target vessel revascularization) at 1, 9 and 12 months after treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Late lumen loss at 9 months follow-up by quantitative coronary angiography. | — |
Contacts
Public ContactJ. Klijn
Diagram B.V. Zwolle Dokter Stolteweg 96
Outcome results
None listed