Immune effects of acidic and neutral oligosaccharides in the nutrition of preterm infants: CARROT study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON27978

Enrollment

108

Registered

2007-02-01

Start date

2007-04-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prebiotics, Immune effects, Gastrointestinal tract, preterm infants Prebiotica, Immuunsysteem, Maagdarmkanaal, Tevroeggeboren kinderen

Interventions

Enteral supplementation of acidic and neutral oligosaccharides (20%/80% mixture) in a maximum doze of 1.5g/kg/day during the first month of life.

Eligibility

Inclusion criteria

Inclusion criteria: Infants born with a gestational age of less than 32 weeks and/ or a birthweight of less than 1500 gram

Exclusion criteria

Exclusion criteria: 1. Severe congenital disorders, like cardiac disorders, syndromal disorders, immunodeficiency disorders; 2. Congenital disorders of the gastrointestinal tract.

Design outcomes

Primary

Measure	Time frame
1. The effect of acidic and neutral oligosaccharides supplemented enteral feeding on infectious morbidity; 2. The incidence of serious infections, using the previously described criteria for serious infections in preterm infants at high risk for serious infections, are prospecitively documented from birth till discharge home.	—

Secondary

Measure	Time frame
1. The effect of acidic and neutral oligosaccharides supplemented enteral nutrition on feeding tolerance, short-term outcome, postnatal adaptation of the gut and modulation of the immune response	—

Contacts

Public ContactRuurd M. Elburg van

VU University Medical Center Dept of Pediatrics PO Box 7057

rm.vanelburg@vumc.nl+3120-4442413

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)