ADOLESCE-NT Studie.

More rapid deterioration of renal function after renal transplantation in adolescence: effect of the endocrine system on immunological and pharmacokinetic factors.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON27975

Enrollment

125

Registered

2012-06-11

Start date

2012-04-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney transplant, children, adolescents, rejection, transplant survival

Interventions

1. Blood drawn by venous puncture

2. X-ray of the hand

3. Determining puberty stage

4. Mini-questionaire.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients planned for renal transplantation, or after renal transplantation; 2. Age 10 – 25 years.

Exclusion criteria

Exclusion criteria: 1. No informed consent given; 2. Treatment with rituximab or chemotherapy; 3. Pubertas precox (puberty before the 8th year of life).

Design outcomes

Primary

Measure	Time frame
The relationship of the endocrine status (serum hormonal levels and skeletal age) and immunological status.	—

Secondary

Measure	Time frame
The relationship of the endocrine status and pharmacokinetic parameters.	—

Contacts

Public ContactK.M.E. Meys

Sophia kinderziekenhuis - Erasmus MC Dr. Molewaterplein 60

k.meys@erasmusmc.nl+31 (0)10 7038292

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)