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ULTRA-stroke.

Upper limb training after stroke: Contrasting the clinical effects and underlying mechanisms of unilateral and bilateral training.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON27945
Enrollment
60
Registered
2009-02-06
Start date
2009-03-30
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke, beroerte, neurorehabilitation, neurorevalidatie.

Interventions

1. Constrained Induced Movement Therapy (CIMT)
3 times a week 1 hour, for 6 consecutive weeks
2. Bilateral Arm Training with Auditory Cueing (BATRAC)
3. Dose-Matched Control Therapy (DMCT)
3 times a week 1 hour, for 6 consecutive weeks.

Sponsors

VU Faculty of Human Movement Sciences, VU University Medical Center, Department of Rehabilitation Medicine, MOVE, Rehabilitation Centre Amsterdam
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. First-ever ischemic or hemorrhagic stroke in one of the hemispheres within the previous 6 months; 2. Upper limb deficit; 3. 18 to 80 years of age; 4. Motivated to participate; 5. Give written or oral informed consent.

Exclusion criteria

Exclusion criteria: 1. Suffer from upper extremity orthopaedic limitations that may affect the results; 2. Not being able to communicate; 3. Disoriented with regard to time and place; 4. Pacemaker or other metallic implants.

Design outcomes

Primary

MeasureTime frame
1. Action Research Arm test (ARAT); 2. Patterns of correlated cortical activity in original and contralateral target areas and changes in spectral power in specific frequency bands; 3. Neuromechanics, i.e. stiffness, motor function (paresis) and control (reflex gains and modulation) around wrist joint; 4. Contribution of sources (feedforward, error correction, and fase entrainment) of interlimb interactions.

Secondary

MeasureTime frame
1. Motricity Index; 2. Nine Hole Peg test; 3. Brunnstrom Fugl Meyer arm-hand test; 4. Nine hole peg test; 5. Erasmus MC modification of Nottingham sensory assessment; 6. Stroke impact scale 3.0; 7. Motor activity log.

Contacts

Public ContactL. Delden, van
l.vandelden@fbw.vu.nl+31 (0)205988495

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)