Surgery Colonoscopy Colorectal adenoma Colorectal polyp Chirurgie Coloscopie Colorectaal adenoom Colorectale poliep
Conditions
Interventions
There are no formal interventions, since this is a retrospective multicenter cohort study in order to investigate the volume of performed colorectal surgery for benign colorectal polyps in the past de
Sponsors
Academic Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: We will retrospectively include all patients who were treated with surgical resection of their benign large colorectal lesion in the regional hospitals and academic centers in the province of North-Holland. In order to be eligible to be included in this study a patient must meet all of the following criteria: - The patient underwent colorectal surgery between 2005 and 2015 in one of the participating hospitals for at least onea: - Colorectal polyp with benign histopathology, defined as a tubular, tubulovillous or villous adenoma or sessile serrated adenoma/polyp with low grade or high grade dysplasia, sessile serrated lesions or traditional serrated lesions with or without (high or low grade) dysplasia and hyperplastic polyps.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from inclusion in this study: - Clear signs of submucosal invasion at histopathology of the resection preparation - Known with Inflammatory Bowel Disease - Known with polyposis syndromes, like Familial Adenomatous Polyposis, Lynch Syndrome and Serrated Polyposis Syndrome - Surgery for synchronous colorectal malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our main study endpoint is the overall volume of colorectal surgery as the treatment for benign colorectal polyps and volume changes in the past decade. | — |
Secondary
| Measure | Time frame |
|---|---|
| The following secondary study parameters are designed to further study the polyp, surgical and pre surgical endoscopy characteristics. - Indications for surgical resection - Reason for referral for surgical resections - Types of surgery performed - Complication and mortality rate associated with benign colorectal surgery - Polyp location - Mean polyp size - Polyp morphology - Endoscopic diagnosis during endoscopy - Histopathologic diagnosis after surgery in the resection preparation - Diagnosis made by gastroenterologist, surgeon or internist for referral for surgery. - Indication for the colonoscopy that identified the large colorectal lesion - Number of colonoscopies performed before referral for surgical resection - Number of endoscopic polypectomy procedures - Number of endoscopic polypectomy attempts after referral to a tertiary center - Complication rate and mortality associated with colonoscopy | — |
Contacts
Public ContactMaxime E.S. Bronzwaer
Meibergdreef 9
Outcome results
None listed