Turner syndroom (Syndroom van Turner)The main study parameters are: height, body proportions, body composition, symptoms and signs of virilization, glucose tolerance, lipid profile, cardiac conduction abnormalities, liver and thyroid function, (neuro)psychological function and quality of life.
Conditions
Interventions
Participating subjects are investigated during a single, whole-day visit to the RUNMC which comprises of standardized history taking and physical examination including standardized photographs, sampli
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1. Completion of the original TOS protocol at least 6 months prior to the study visit; 2. Age >18 years.
Exclusion criteria
Exclusion criteria: 1. Patients who have participated in another experimental drug study within two months of entry into the present study; 2. Malignant or severely disabling disease; 3. Serious suspicion of psychiatric illnesses; 4. Pregnancy or current fertility treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Final adult height. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Body proportions and composition; 2. Metabolic parameters; 3. Virilizing effects; 4. Cardiovascular, liver and thyroid function; 5. (Neuro)psychological function; 6. Quality of life. | — |
Contacts
Public ContactHJLM Timmers
Radboud University Nijmegen Medical Centre, Department of Endocrinology 471 P.O. Box 9101
Outcome results
None listed