Inflammatory bowel disease, iron deficiency anemia
Conditions
Interventions
All procedures are performed by endoscopists experienced with the balloon assisted enteroscopy technique. Sedation is given according to current standards. Oral enteroscopy is always performed first,
Sponsors
Erasmus Medical Center, Department of Gastroenterology and Hepatology
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients known with CD and suspted small bowel disease activity; 2. Patients with iron deficiency anemia (control subjects); 3. Age 18 years or older.
Exclusion criteria
Exclusion criteria: 1. Under 18 years of age; 2. Medical and psychological contraindications for balloon assisted enteroscopy; 3. Patients unable or not willing to give informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint: Comparison of NBI enteroscopy with white light in detection and grading of Crohn's disease inflammation in small bowel. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints: 1. Correlation of endoscopic findings with clinical findings; 2. Correlation of endoscopic findings with conventional histopathology; 3. Correlation of endoscopic findings with immunohistochemical analysis of immunocompetent cells and mRNA levels of proinflammatory cytokines. | — |
Contacts
Public ContactH. Aktas
Outcome results
None listed