Schizophrenia, schizoaffective disorder, schizophreniform disorder
Conditions
Interventions
None listed
Sponsors
Prof. Dr. I.E.C. Sommer
Eligibility
Inclusion criteria
Inclusion criteria: 1. The participant understands the study and is able to provide written informed consent 2. Must be between the ages of 26-40 3. For patients: must have a diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder 4. For siblings: must have 1 brother or sister with a disorders specified under point 3. The sibling is not necessarily related to one of the participants from the patient group. 5. For controls: participants must be free of any psychiatric or neurological disease and should not have any first- or second-degree relatives with one of the disorders specified under point 3.
Exclusion criteria
Exclusion criteria: 1. Participation in a scientific research study during the past year involving radiation (or exposure to the same amount of ratiation within the past year via other means, e.g., transatlantic flights) 2. MR incompatible implants in the body 3. The possibility of having metal particles in the eyes 4. Tattoo’s containing red pigments that form a safety risk 5. Inability to undergo cognitive testing in Dutch 6. Dangerous or harmful behaviour (i.e. behaviour with a risk of severe physical injury, or actual physical injury inflicted, to self or others) occurred in last 3 months 7. Possibility of pregnancy 8. Intake of levetiracetam or brivaracetam
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the relationship between synaptic density and cognitive functioning and the potentially mediating role of functional connectivity in this relationship. | — |
Contacts
Public ContactMonique Germann
University Medical Center Groningen
Outcome results
None listed