Slowly progressive neuromuscular diseases
Conditions
Interventions
None
Sponsors
Amsterdam UMC
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - presence of slowly progressive NMD. - ability to perform a maximal exercise test on an arm or bicycle ergometer. - minimum age of 18 years.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - absolute contraindication for exercise (based on the guidelines by the American College of Sports Medicine) - unable to follow verbal or written instructions. - insufficient mastery of the Dutch or English language.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Validity of statistical model to determine the anaerobic threshold out of easy to measure indirect variables (heart rate variability, rating of perceived exertion, Talk Test, age, gender, resting heart rate) | — |
Secondary
| Measure | Time frame |
|---|---|
| - The percentage of times that the AT can be determined through submaximal exercise testing with respiratory gas analysis - The test-retest reliability of the heart rate at the anaerobic threshold determined through submaximal exercise testing with respiratory gas analysis | — |
Contacts
Public ContactTim Veneman
Amsterdam UMC, locatie AMC
Outcome results
None listed