Neural plasticity, hearing loss and tinnitus: changes in tonotopic maps of the auditory cortex

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON27684

Enrollment

120

Registered

2014-09-24

Start date

2015-01-01

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hearing loss tinnitus tonotopy auditory cortex

Interventions

fMRI measurements while listing to sound fragments.

Eligibility

Inclusion criteria

Inclusion criteria: - No hearing loss or reported tinnitus (controls, n=40) - Hearing loss (Hearing loss group, n=40) - Tinnitus (Hearing loss and tinnitus group, n=40) - < 30 dB difference between both ears for all the standard audiometric frequencies - Adults (18 - 75 yrs.) - No contraindications for MRI

Exclusion criteria

Exclusion criteria: Non-compliance with inclusion criteria

Design outcomes

Primary

Measure	Time frame
Measures of tonotopic map reorganisation.	—

Secondary

Measure	Time frame
Relation of hearing loss and degree of reorganisation. Two types of hearing loss are going to be studied: steep-sloping hearing loss and gradual sloping hearing loss.	—

Contacts

Public ContactC.P. Lanting

c.p.lanting@umcg.nl050 363 5111

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)