Respiratory complaints
Conditions
Interventions
One extra blood sample will be obtained with the standard venepuncture or from the peripheral venous catheter to collect the venous blood gas. No extra vascular puncture is required.
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: Patients (= 18 years) presenting in the ED with dyspoea, respiratory rate > 20/min or peripheral oxygen saturation <95%, a reliable saturation measured by pulse oximetry and an indication, determined by the treating physician, to determine the acid-bae, ventilation and oxygenation status by arterial blood gas.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Not capable to give informed consent within reasonable time after stabilisation and abating of the accompanying psychological stress, and no representative availabe to give informed consent on behalf of the patient. - Arterial blood gas results are required for other reasons than determining the acid-base, ventilation and oxygenation status, such as determing the alveolar to arterial oxygen gradiënt (A-a gradient). - No physician or qualified nurse available for ABG sampling. - Failed ABG or VBG sampling after two attempts. - Previous participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is the frequency of alterations in treatment of patients with respiratory complaints in the emergency department (ED) based on venous blood gas (VBG) results compared to treatment based on arterial blood gas (ABG) results. We will assess which alterations in treatment occur, the characteristics of alterations and which ABG resuls cause the change. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are the agreement between venous and arterial pH, bicarbonate, pCO2, lactate and pO2 and the correlation between venous and arterial pO2 and the peripheral oxygen saturation measured with pulse oximetry. | — |
Contacts
Public ContactSarah Körver
Zuyderland Medisch Centrum
Outcome results
None listed