Sialorrhea, drooling, Parkinson Disease. Speekselvloed, kwijlen, Ziekte van Parkinson
Conditions
Interventions
The participant will use 4 different dosing regimes of glycopyrronium inhalation powder. Three times a day a drooling score must be filled. Patients must record adverse events and other special events
Sponsors
Medisch Spectrum Twente, Enschede
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosed with Parkinson disease Moderate to severe sialorrhea, defined as a minimum of 4 of the Mier scale Age > 18 years Able to fill the scoring table (or the partner/carer must be able to)
Exclusion criteria
Exclusion criteria: Hypersensitivity to glycopyrronium or other excipients Use of medication with known anticholinergic effects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The safety and tolerability of glycopyrronium inhalation powder in patients diagnosed with sialorrhea and parkinson disease, measured in adverse events and other special events that occur. | — |
Secondary
| Measure | Time frame |
|---|---|
| Het mean difference in drooling between different dosing regimes and the patient preference. | — |
Contacts
Public ContactJ.B. Masselink
Koningsplein 1, Enschede
Outcome results
None listed