Thumb base osteoarthritis
Conditions
Interventions
Sponsors
ZonMW
Eligibility
Inclusion criteria
Inclusion criteria: All participants must meet the following criteria: 1) age = 18 years; 2) Eaton(35) stage 2-3 CMC-1 OA based on radiographics & clinical examination; and 3) ability to visit the treatment center for treatment sessions.
Exclusion criteria
Exclusion criteria: A potential participant that meets any of the following criteria will be excluded: 1) secondary CMC-1 OA (e.g., due Bennett’s fracture); 2) presence of comorbidity that interferes with treatment or outcome (e.g., carpal tunnel syndrome or De Quervain tenosynovitis); 3) surgery in medical history that interferes with treatment or outcome (e.g., trapeziectomy or tendon repair); 4) steroid injection in hand/wrist <6 weeks prior to admission; 5) previous treatment for CMC-1 OA in one of both hands, including orthosis, hand therapy or surgery; or 6) insufficient ability to understand written and spoken Dutch or English language.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain (3mo) and conversion to surgery (12 mo) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Health related quality of life (EQ-5D) - Hand function/ADL (MHQ) - Patient satisfaction with treatment result (ICHOM self-designed) - Return to work (ICHOM self-designed) - Grip & pinch strength (Jamar, key pinch and tip pinch) - Thumb ROM (goniometry and inter metacarpal distance), - Reported experience - Complications (all complications are classified and registered throughout the trial) - Costs & productivity loss (iPCQ) - Treatment adherence (therapy adherence assessment tool) - Treatment credibility and expectations (CEQ) - Perceived attention/quality of the relationship (CARE) - Psychological factors, including anxiety & depression (PHQ), Illness perception (brief-IPQ) and pain catastrophizing (PCS) | — |
Contacts
Public ContactRobbert Wouters
Erasmus MC Rotterdam
Outcome results
None listed