chronic pain electrocutaneous stimulation evoked potential nociception
Conditions
Interventions
The participants will be asked to come to the Human Physiology Lab of the BSS Group at the University of Twente for one session. First, the participant is familiarized with the stimuli by stepwise app
Sponsors
University of Twente, Biomedical Signals and Systems Group
Eligibility
Inclusion criteria
Inclusion criteria: Age between 18 and 40 years old.
Exclusion criteria
Exclusion criteria: Participant refusal during the study. • Language problems. • Skin problems at site of stimulation or EEG recording. • Diabetes. • Implanted stimulation device. • Pregnancy. • Usage of analgesics within 24 hours before the experiment. • Consumption of alcohol or drugs within 24 hours before the experiment. • Pain complaints at the time of the experiment. • A medical history of chronic pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of this study is to describe the quality and content of electrical brain responses of pain free subjects to electrocutaneous stimuli during multiple threshold tracking, by determining the signal-to-noise ratio of averaged responses and by exploration of the use of generalized linear mixed models to explain the variability in these responses. The data will be used for computation of a linear mixed-model describing the influence of stimulus parameters on the nociceptive evoked potential. | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis to determine if and how the EEG signal is dependent on stimulus properties like the inter-pulse interval, stimulus amplitude and stimulus detection. | — |
Contacts
Public ContactB. Berg, van den
Outcome results
None listed