Patients with a primary diagnosis of osteoarthritis and scheduled for an elective unilateral total knee arthroplasty (TKA)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: • Patients 18 years or older • Symptomatic knee osteoarthritis according to the American College of Rheumatology classification criteria (Wu et al, 2005). Radiographic disease severity will be evaluated for each participant (Kellgren-Lawrence 0-4 grading scale). • Scheduled for an elective unilateral total knee arthroplasty (TKA) no sooner than 2 weeks from the time of recruitment • Be able to understand and speak Dutch language • Patient is willing and able to complete scheduled study procedures and follow-up evaluations. • Provide written informed consent
Exclusion criteria
Exclusion criteria: • Scheduled for revision arthroplasty • Diagnosis of inflammatory arthritis (i.e. rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosis, ankylosing spondylitis) • Scheduled for TKA because of a fracture, malignancy or an infection; • Patient is currently participating in any other surgical intervention studies or pain management studies • Previous total knee arthroplasty or any other lower limb surgery within the past six months • Cognitive impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary clinical outcome is pain at 3 months after TKA surgery. The Western Ontario and McMaster Universities Osteoarthirits Index (WOMAC-DV), subscale pain, will be used as pain specific instrument. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pain levels 12 months after surgery in patiens undergoing TKA 2. Physical functioning 3 and 12 months post-operative 3. Stiffness 3 and 12 months post-operative 4. Health related quality of life 3 and 12 months post-operative 5. Attention to pain 3 and 12 months post-operative 6. Pain catastrophizing 3 and 12 months post-operative 7. Anxiety and depression 3 and 12 months post-operative | — |
Contacts
Tergooi Hospital