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Food preference.

Representation of food preference in the brain in relation to visceral obesity and stress.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON27486
Enrollment
40
Registered
2009-07-10
Start date
2009-09-15
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Visceral obesity, stress

Interventions

1. Stressed condition: The stressed condition is a situation where the subjects are brought in a state of actual mental stress. The control condition is a condition of rest applied to the same subjec

Sponsors

NUTRIM, Maastricht University, Maastricht, The Netherlands Top Institute Food and Nutrition, Wageningen, The Netherlands
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Right-handed; 2. Both genders; 3. Age between 18-55 years; 4. BMI between 20 and 25 kg/m2 and between 25 and 30 kg/m2 with a waist circumference for men > 90 cm and for women > 80 cm; 5. Liking the tested food items; 6. Being able to play a standard memory game; 7. Without any metals in the body. Because of the different brain laterality in left- and right-handed subjects we chose to include only right-handed subjects. Hence the results can be compared between the subjects. Determining the effect of age is not an aim of this study. For the purpose of simplicity we exclude the effect of ageing and therefore set the age limit at 55 years.

Exclusion criteria

Exclusion criteria: 1. Having metals in the body; 2. Having a food allergy; 3. Not being able to play a standard memory game; 4. Being left-handed; 5. Diabetics; 6. Use of medication (except contraception); 7. Extensive alcohol consumption (more than 10 consumptions per week); 8. Instable weight; 9. Pregnancy; 10. Claustrophobia; 11. Depression; 12. Other serious disorders (for example epilepsy, arrhythmia, parkinsonism, insomnia); 13. A past history of psychiatric disorders.

Design outcomes

Primary

MeasureTime frame
The main study endpoint is the effect of acute and long-term consumption of highly rewarding foods on the physiological stress response and relevant reward related brain areas, on rewarding value of other foods and food intake in visceral overweight subjects.

Contacts

Public ContactMS Westerterp-Plantenga

Maastricht University Dept. Humane Biology PO Box 616

M.Westerterp@hb.unimaas+31 43 3881566

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)