Incidence of colorectal lesions in first degree relatives of patients with serrated polyposis syndrome.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON27458

Enrollment

Registered

2012-01-19

Start date

2008-12-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

serrated polyposis syndrome, hyperplastic polyposis syndrome, sessile serrated adenoma, colorectal cancer, CRC

Interventions

All eligble FDRs are invited to undergo a standard white light screening colonoscopy.

Eligibility

Inclusion criteria

Inclusion criteria: First degree relatives (>35 years of age or 5 years younger than the lowest incidence age) of SPS patients under surveillance at the endoscopy department.

Exclusion criteria

Exclusion criteria: 1. Individuals who have undergone a colonoscopy in the past three years; 2. Indivuals who have undergone a colectomy; 3. Severe co-morbidity; 4. Incomlpete colonoscopy; 5. Poor bowel preparation.

Design outcomes

Primary

Measure	Time frame
The incidence of CRC, adenoma detection rate (ADR) and presence of multiple (>2) proximal serrated polyps (HPs or SSAs).	—

Secondary

Measure	Time frame
The incidence of complications.	—

Contacts

Public ContactY. Hazewinkel

Meibergdreef 9

y.hazewinkel@amc.uva.nl+31 (0)20 5662806

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)