Glutathione Metabolism in Neonates.

Glutathione kinetics and oxidative stress in preterm infants.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON27445

Enrollment

200

Registered

2005-09-06

Start date

2005-08-11

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Preterm infants are resuscitated with different oxygen concentrations at birth.

Eligibility

Inclusion criteria

Inclusion criteria: Preterm infants with gestational age < 32 weeks.

Exclusion criteria

Exclusion criteria: Known congenital abnormalities, chromosome defects, metabolic disease, and endocrine, renal, or hepatic disorder.

Design outcomes

Secondary

Measure	Time frame
1. Concentration of oxidative stress markers, Apgar Score, oxygen saturation and heart rate in first 20 minutes after birth; 2. Mortality; 3. The incidence of bronchopulmonary dysplasia.	—

Primary

Measure	Time frame
Glutathione synthesis rate.	—

Contacts

Public ContactD. Rook

Erasmus MC - Sophia Children's Hospital c/o room SP-3433

d.rook.1@erasmusmc.nl+31 (0)10 7037008/ +31 (0)10 7040704

Outcome results