autismespectrumstoornis, autism spectrum disorder, persoonlijkheidsstoornis, personality disorder
Conditions
Interventions
To decide if a person can or can not participate in one of the three groups, a questionnaire for general information about primary diagnosis, age, education, marital status etc. and the SCID-5-SPQ (Fi
First et al. 2016b) will be administered to all participants (n = 90). All interviewers and observers are well trained and educated in at least ASD in adults, and in the NIDA by the study author, in t
Sponsors
Sarr Expertisecentrum Autisme
Oudedijk 76
3062 AG Rotterdam
088-3585500
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for the ASD group are a primary diagnosis of DSM-IV Autistic Disorder or Asperger’s Disorder, and/or DSM-5 ASD, with or without a comorbid DSM-IV/5 personality disorder (PD), male gender, age ≥ 18 years, and no intellectual disability), at least a completed primary school and secondary education, and being able to state and/or recognize own (psychological and problematic) functioning. We will solely include males as males are diagnosed with ASD 3 to 4 times more than females. The diagnosis ASD (including AD and AS) will be verified by studying the diagnostic report including the diagnosis ASD based on clinical evaluation of autism-specific behaviors by direct observation of the patient and report of developmental and behavioral history and current functioning obtained by partner, parent or mentor. The ASD must be diagnosed in a multidisciplinair team consisting of at least a registered psychologist or psychiatrist. A possible comorbid PD must be assessed with the Dutch version of the Structured Clinical Interview for DSM-IV Axis II or DSM-5® Personality Disorders (SCID-II; First et al. 1997; SCID-5-PD; First et al. 2016a). Inclusion criteria for the PD group are a primary diagnosis of DSM-IV and/or DSM-5 PD, assessed with the Dutch version of the SCID-II (First et al. 1997) or SCID-5-PD (First et al. 2016a), no past or current suspicion by health care professionals of and no diagnosis of DSM-IV/DSM-5 ASD, male gender, age ≥ 18 years, no intellectual disability, at least a completed primary school and secondary education, and being able to state and/or recognize own (psychological and problematic) functioning. Inclusion criteria for the non-ASD/non-PD group are no ASD and no PD diagnosis, male gender, age ≥ 18 years, no intellectual disability, at least a completed primary school and secondary education, having a reasonable degree of insight into and recognition of their (psychological) functioning.
Exclusion criteria
Exclusion criteria: Exclusion criteria for all participants are intellectual disability (IQ < 80), female gender, and presence of current suicidal ideation, and those who have been diagnosed ASD with the NIDA in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In order to answer the main research question ‘Is the NIDA a methodologically sound instrument for diagnosing ASD in adults?’, the following instruments will be used: NIDA, ADOS, SCID-5-PD interview and SCID-5-SPQ In order to answer the first research question ‘Does the NIDA have a good interrater reliability?, we study the correlation of the outcomes on the eight questions of the NIDA between the interviewer and the observer, independently judging the item scores for current functioning on this instrument. | — |
Secondary
| Measure | Time frame |
|---|---|
| In order to answer the second research question ‘Does the NIDA have a good convergent validity?’, we study the outcomes (yes ASD, no ASD) on the ASD assessment. With respect to the NIDA we will first use the sum score of 3 for questions 1-3 and sum score of ≥2 for questions 4-7 for current functioning. The combination of these sum scores will lead to yes or no current ASD. We compare this combination (yes or no current ASD) with ADOS total score of ≥8 or ≥10 (yes current ASD). Second, we will compare the combination of the sum scores of the eight questions for current functioning of NIDA (yes or no current ASD) to the clinically diagnosed ASD (yes for current ASD). In order to answer the third research question ‘Does the NIDA have a good discriminant validity?’, we use the NIDA, SCID-5-PD interview and the SCID-5-SPQ screening tool. We use the total sum scores for current functioning on the NIDA to allocate the participants into one of the three groups (ASD, PD without ASD, and COM), expecting higher total sum scores for participants with ASD than for participants with PD without ASD, and COM. The SCID-5-PD interview and SCID-5-SPQ will be used to diagnose PDs. | — |
Contacts
Public ContactVuijk
Sarr Expertisecentrum Autisme
Outcome results
None listed