Barrett's esophagus, (low/high grade) dysplasia, esophageal adenocarcinoma
Conditions
Interventions
None listed
Sponsors
University Medical Center Groningen (UMCG)
Eligibility
Inclusion criteria
Inclusion criteria: o Patients with established BE scheduled for gastroscopy due to surveillance examination; o Patients with established BE and a malignant visible lesion scheduled for gastroscopy due to endoscopic mucosal resection (EMR) or Endoscopic Submucosal Dissection (ESD). o Age = 18 years; o Written informed consent.
Exclusion criteria
Exclusion criteria: o Age younger than 18 years o Inability to give written informed consent for the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy is defined as sensitivity, specificity, predictive value and likelihood ratio’s. Measures: true positives, true negatives, false positives and false negatives of endocytoscopy procedure. Gold standard for comparison is the histopathological result of biopsy which will be extracted from reports of patients’ digital medical chart for which they will have to provide consent. | — |
Secondary
| Measure | Time frame |
|---|---|
| Kappa values for inter-observer agreement. Procedural qualities will consist of the rating of image quality and additional procedural time for making endocytoscopic images. Basic demographic data: gender, year of birth. | — |
Contacts
Public ContactJouke van der Laan
Universitair Medisch Centrum Groningen
Outcome results
None listed