rhinovirus rhinovirus cardiac surgery hart operatie respiratory infection respiratoire infectie post operative complications post operatieve complicaties
Conditions
Interventions
The parents/guardians of the children will be asked to fill out a questionnaire before the operation of their child. In the operating theatre, a nasopharyngeal swab will collected in the children afte
Sponsors
Drs. P.P. Roeleveld
Leiden University Medical Center (LUMC)
Department of paediatric Intensive Care
Dr. J.J.C. de Vries
Leiden University Medical Center (LUMC)
Department of Medical Microbiology
Eligibility
Inclusion criteria
Inclusion criteria: • Children (<12 year) with a congenital heart disease undergoing elective cardiac surgery • Written informed consent by parents or guardian
Exclusion criteria
Exclusion criteria: • No informed consent from one of the parents (or the legal representative if applicable) • Anaesthesiologist or cardiopulmonary surgeon postpones surgery based on routine hospital screening • Emergency surgery • Pre-operative admission to the neonatology department • Children not admitted to the intensive care unit after cardiac surgery • Children undergoing a second cardiac operation during the same intensive care stay • Children with duct-dependent physiology who remain prostaglandin-dependent after the heart operation (they will be excluded because they will certainly have a prolonged PICU LOS regardless of a possible rhinovirus infection). For example: hypoplastic left heart syndrome following pulmonary artery banding who will remain on prostaglandins until the next staged operation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study parameter is post-operative PICU length of stay in rhinovirus positive compared to rhinovirus negative patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome parameters are: • Duration of ventilatory support • Mechanical ventilation conditions (mean airway pressure, FiO2) • Antibiotic free days (alive at PICU discharge) • Need of inotropes (inotrope score) • Infection parameters • Hospital length of stay • Secondary infections | — |
Contacts
Public ContactR.B.P Wilde
departmet of intensive care
Outcome results
None listed