ALI, ARDS, eNOSE, sepsis, mechanical ventilation. ALI, ARDS, eNOSE, sepsis, beademing.
Conditions
Interventions
No interventions, diagnostic study.
Sponsors
Academic Medical Center (AMC), Departments of Pulmonology and Intensive Care.
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with established ALI/ARDS according to the American/European Consensus Criteria 2. Patients at risk for developing ALI/ARDS 3. Patients without lung injury, not at risk for developing ALI/ARDS and not known to a have pre-existent pulmonary condition
Exclusion criteria
Exclusion criteria: 1. Younger than 18 years of age 2. Pregnancy 3. Current malignancy 4. Use of steroids in higher than hysiologic dosages (300 mg hydrocortisone or equivalent) 5. Recent cardiopulmonary surgery (reason for admittance)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electronic nose smellprint. Exhaled air is collected via a connector in the circuit of the mechanical ventilator near the tube and, if present, proximal to the filter. The connector is attached to the electronic nose (Cyranose 320) and measurements are taken for 60 seconds. When exposed to a gas mixture, the sensors of the electronic nose will swell and thus change the electrical conductance, resulting in a unique smellprint. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Lung injury score. | — |
Contacts
Public ContactNiki Fens
Clinical Research Fellow 'Electronic Nose' Academic Medical Center (AMC) University of Amsterdam Department of Pulmonology F5-260 P.O.Box 22660
Outcome results
None listed