Androgens, ovaries, female-to-male transsexuals
Conditions
Interventions
Standard androgenic treatment as part of their sex-reassignment hormonal therapy.
Sponsors
VU University Medical Center, Amsterdam the Netherlands.
Department of Obstetrics and Gynaecology in collaboration with the department of Gender Dysphoria of the VU University Medical Center.
Eligibility
Inclusion criteria
Inclusion criteria: - Diagnosis Gender Dysphoria - >1 year cross-sex hormonal treatment - Age 18+ - Intention to undergo sex-reassignment surgery
Exclusion criteria
Exclusion criteria: - Disorder of sexual development - Concomitant pathology with known or possible endocrine effects - Excessive alcohol or drug abuses - Patients who explicitly declare that they do not want to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian morphology, in terms of: - transvaginal ultrasound - histopathological features | — |
Secondary
| Measure | Time frame |
|---|---|
| Predisposition towards hyperandrogenism and reproductive alterations in gender dysphoric (GD) individuals, and are polycystic ovaries more likely in GD females? | — |
Contacts
Public ContactM.R. Caanen
Arts-onderzoeker Afdeling Voortplantingsgeneeskunde (Gynaecologie en Obstetrie) VU Medisch Centrum Gebouw Zuid, F 16 Postbus 7057 1007 MB Amsterdam
Outcome results
None listed