Indocyanine green dye in surgical treatment of laryngeal cancer

Indocyanine green dye in surgical treatment of laryngeal cancer: perfusion assessment to identify patients at risk for complications

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON27297

Enrollment

Registered

2020-11-10

Start date

2021-06-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laryngeal cancer

Interventions

By using IOLA-ICG, we will measure perfusion of pharyngeal mucosa and skin of the neck in 30 patients with PTL, STL or neck dissection for LC. The perfusion data will be correlated with development of

Eligibility

Inclusion criteria

Inclusion criteria: - Proven carcinoma of the larynx - > 18 years of age - Undergo a PTL or STL with or without neck dissection or undergo neck dissection for LC - Informed consent - Patients are mentally competent

Exclusion criteria

Exclusion criteria: - Partial laryngectomy - Pregnancy - Patients with known allergy against ICG or iodine/shellfish - Patients with hyperthyroidism or thyroid gland adenoma - Patients with dialysis dependent renal failure and/or kidney transplant

Design outcomes

Primary

Measure	Time frame
We want to estimate cut off values for clinically appropriate hypoperfusion of the pharyngeal mucosa and the skin in the neck.	—

Secondary

Measure	Time frame
We want to compare perfusion rate of PTL to perfusion rate in STL in order to create cut off values for both patient categories.	—

Contacts

Public ContactConstanze Scholman

Universitair Medisch Centrum Groningen

c.scholman@umcg.nl(050) 361 61 61

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)