cerebrovascular accident stroke beroerte
Conditions
Interventions
group A1: good prognosis: Constraint Induced Movement Therapy (CIMT) for 3 consecutive weeks, 5 days a week versus conventional therapy
group A2: poor prognosis:
Elektromyography-triggered neuromu
Sponsors
ZON MW
Eligibility
Inclusion criteria
Inclusion criteria: 1. First ever ischemic lesion in territory of MCA 2. Mono- or hemiparesis (NIHSS item 5a&b score 1-4) 3. Age 18-80 4. Able to comprehend and communicate 5. Able to sit for 30 s without support 6. Motivated to participate in an intensive rehabilitation treatment programme for 3 weeks 7. Written or oral informed consent
Exclusion criteria
Exclusion criteria: 1. Trombolysis (rTPA, alteplase) with positive effect 2. Pacemaker or metallic implants 3. Orthopaedic limitations of upper extremity 4. Not being able to communicate 5. Botuline toxine or medication that may influence upper limb function in previous 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - ARAT (A projects) - Focussing of cortical activity in original target area (fMRI, B1 project) - Integrity of corticospinal tract (TMS) - Trunk movement in standard reaching task (B2 project) - Neuromechanics, i.e. stiffness, motor function (paresis) and control (reflex gains and modulation) around wrist joint (B3 project) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Modified Ashworth score - Wolf motor function test - Frenchay arm test - Motoricity index - Brunnstrom Fugl Meyer arm-hand test - Nine hole peg test - Erasmus MC modification of Nottingham sensory assessment - Stroke impact scale 3.0 - Nottingham extended ADL - Motor activity log - O-letter cancelation test - Barthel index | — |
Contacts
Public ContactJ.H. Arendzen
Leiden University Medical Center (LUMC) Department of Medical Rehabilitation P.O. Box 9600
Outcome results
None listed