Hemodialyse Hemodialysis Fysieke inspanning Exercise Eiwit Protein Aminozuren Amino Acids
Conditions
Interventions
During four hemodialysis sessions, patients will (A) ingest a placebo drink, (B) ingest a placebo drink and perform aerobic exercise, (C) ingest a protein supplement, and (D) ingest a protein suppleme
Sponsors
Maastricht University Medical Centre+
Eligibility
Inclusion criteria
Inclusion criteria: - Aged >18 years - Ability to provide written informed consent - Hemodialysis treatment for >3 months - Well-functioning arteriovenous shunt in upper or lower arm
Exclusion criteria
Exclusion criteria: – Unstable cardiac status (i.e. cardiac ischemia) – Physical limitations affecting usage of the bike – Poor blood sugar control – Active infection or illness – Poorly functioning shunt – Previous episodes of intradialytic hypotension related to food intake – Hospitalization <3 months prior to study period – Missed hemodialysis session <1 month prior to study period – Allergies to milk protein
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary study parameters are amino acid loss into the dialysate and plasma total amino acid concentrations. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters are the loss of essential amino acids into the dialysate, plasma essential amino acids, glucose, and insulin concentrations, interstitial glucose concentrations, plasma and spent dialysate uremic toxin concentrations, and changes in blood pressure. | — |
Contacts
Public ContactF.K. Hendriks
Maastricht Univeristy
Outcome results
None listed