Sport-Related Flow-Limiations in the Iliac Artery
Conditions
Interventions
The study is designed as a prospective observational study without any invasive measurements. After written and oral informed consent, t0 and t1 measurements will be performed. If the participant is w
Sponsors
ZonMw: 75020017
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female aged>18; 2. Endurance athlete for at least three years = 5 hours per week of training 3. Unilateral- or bilateral pain, cramp and/or powerlessness in the leg or legs during (sub)-maximal exercise which disappears within a few minutes after ceasing exercise; 4. Proved sport-related flow-limitations as a result of kinking and/or intravascular lesions, diagnosed with duplex-Doppler echography examination For control subjects the same in and exclusion criteria except those regarding to sport-related flow limitations
Exclusion criteria
Exclusion criteria: 1. No operative vascular reconstruction in the iliac region 2. No diagnosed heart failure according to the New-York Heart Association stage>1 3. Cardiovascular risk 4. Atherosclerosis 5. Lumbar herniated discs 6. Complaints do not seem to be restricted to one muscle group or tendon; For control subjects the same in and exclusion criteria except those regarding to sport-related flow limitations
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reproducibility: 1. Difference (paired T-test when normally distributed) 2. Agreement (intra-class correlation coefficients, (ratio) limits of agreement and coefficients of variation, Bland-Altman) Diagnosis: 1. Difference (paired T-test when normally distributed) 2. Model for detecting sport-related flow-limitation (GLM/GLMNET; ROC curve) Posture: 1. Difference (paired T-test when normally distributed) Surgery: 1. Difference (paired T-test when normally distributed) | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlations to ABI and Peak Systolic Velocities | — |
Contacts
Public ContactMartijn van Hooff
Máxima MC
Outcome results
None listed