tDCS and aphasia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON27213

Enrollment

Registered

2014-02-21

Start date

2013-11-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

We will study participants with aphasia, an acquired language disorder caused by stroke. / De participanten van het onderzoek hebben afasie, een niet-aangeboren taalstoornis die door een beroerte (CVA) is ontstaan.

Interventions

The intervention is tDCS (Transcraniele Direct Current Stimulation). We will study whether tDCS has an additional effect in the rehabilitation of aphasia. To investigate this, two groups will be studi

Eligibility

Inclusion criteria

Inclusion criteria: -Aphasia after stroke -Time post onset < 3 months -Age 18-75 years -Right handed -Physical health sufficient to participate in intensive aphasia therapy

Exclusion criteria

Exclusion criteria: -Subarachnoïd Haemorrhage (SAH) -Prior stroke resulting in aphasia -Brain surgery in the past -Epileptic activity in the past 12 months -Excessive use of alcohol or drugs -Insufficient level of Dutch premorbidly -Premorbid (suspected) dementia -Premorbid psychiatric disease affecting communication -Severe non-linguistic cognitive disturbances impeding language therapy -Pace maker -Global aphasia (spontaneous speech 0 AND shortened Token Test 28 AND Boston Naming Test > 150)

Design outcomes

Primary

Measure	Time frame
language functioning i.e. word finding (Boston naming test)	—

Secondary

Measure	Time frame
- Communication. Test: ANTAT - Quality of life. Questionnaires: SAQOL, Euroqol-5D - Care consumption. Questionnaires: Werk en zorg vragenlijst (Health care consumption and labour productivity) - Laterality index. Measurement: fMRI Other outcomes: - demographic data (age, gender, handedness, educational level, socio-economic status) - aphasia type and severity - Size and location of the lesion (fMRI) - Participation: CIQ - overall functioning: Barthel Index - adverse effects: Wong-Baker FACES Pain Rating Scale	—

Measure

Time frame

- Communication. Test: ANTAT - Quality of life. Questionnaires: SAQOL, Euroqol-5D - Care consumption. Questionnaires: Werk en zorg vragenlijst (Health care consumption and labour productivity) - Laterality index. Measurement: fMRI Other outcomes: - demographic data (age, gender, handedness, educational level, socio-economic status) - aphasia type and severity - Size and location of the lesion (fMRI) - Participation: CIQ - overall functioning: Barthel Index - adverse effects: Wong-Baker FACES Pain Rating Scale

—

Contacts

Public ContactK. Spielmann

Kamer MB.014 (afdeling Research & Development) Westersingel 300

KSpielmann@rijndam.nl010 2412412

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)