Peripheral arterial disease (PAD), Peripheral arterial occlussive disease (PAOD), Perifeer vaatlijden, etalage benen
Conditions
Interventions
Standard of care endovascular interventions (if applicable)
Sponsors
St. Antonius Hospital Nieuwegein
Eligibility
Inclusion criteria
Inclusion criteria: I. Age over 18; II. Symptomatic, chronic atheroslcerotic lesions of the common or externa iliac artery; III. Single or multiple borderline (50-70%) stenosis measured with ultrasound IV. Rutherford class 1-6 V. Signed informed consent
Exclusion criteria
Exclusion criteria: I. Mental disability that hinders the ability to understand and comply with the informed consent; II. Pregnancy or breast-feeding; III. Renal insufficiency (e-GFR<30 ml/min/1.73m2); IV. Patients with acute ischemic limbs or aneurismal iliac lesions; V. Patients with intimal dissections; VI. Patients with a combination of low blood pressure (RR) and high heart rate (HR) that might be at risk when inducing pharmacological hyperemia. VII. Patients with occlusive inflow (aortic) and/ or occlusions of the target iliac arteries.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| validation of the MRA or CTA based personalized pre-procedural computer model, with intra-arterial pressure measurements at rest and during pharmacologically induced hyperemia as a reference | — |
Secondary
| Measure | Time frame |
|---|---|
| I. To compare the geometrical information obtained from CTA and MRA with 3D rotational angiography II To quantify the extra radiation, procedure time needed and costs made to determine the hemodynamic significance of iliac artery stenosis by means of invasive pressure measurements as compared to controlled match patient population. | — |
Contacts
Public ContactS.G.H Heinen
St. Antonius Ziekenhuis (Vaatchirurgie)
Outcome results
None listed