Acute appendicitis
Conditions
Interventions
1. Ultra Sound (US)
2. Magnetic Resonance Imaging (MRI).
Sponsors
MCA Alkmaar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Pediatric patients (4-18 years of age) with suspected appendicitis defined as right lower abdominal quadrant pain with or without elevation of CRP; 2. Patients, or a legal representative, must be able to give informed consent, and the consent must be obtained prior to the MR Imaging.
Exclusion criteria
Exclusion criteria: 1. Abdominal surgery in the 6 weeks prior to inclusion; 2. Contra-indication for undergoing MRI, for example presence of a pacemaker or cardioversion device; 3. A psychiatric, addictive, or any disorder that compromises ability to give truly informed consent for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measures are the sensitivity, specificity, positive and negative predictive value and inter observer agreement of MRI in diagnosing acute appendicitis as compared to the reference standard. The MRI findings will be compared to the findings at imaging of the standard diagnostic work-up that preceded MRI (US). The diagnostic value of specific MRI characteristics for appendicitis will be calculated. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are the acceptance of MRI as compared to US by a questionary. | — |
Contacts
Public ContactM.E. Thieme
Medical Center Alkmaar P.O.Box 500
Outcome results
None listed