Hyperplastic polyposis syndrome: Endoscopic treatment and surveillance.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON27090

Enrollment

125

Registered

2011-02-16

Start date

2010-06-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperplastic polyposis CRC serrated adenoma HPSB colorectal carcinoma HPS

Interventions

Data are collected in prospective manner from patients during a routine annual endoscopies with removal of all polyps < 3 mm.

Eligibility

Inclusion criteria

Inclusion criteria: HPS patients defined as: > 5 HPs/SSA proximal to the sigmoid, of which 2 > 10 mm in diameter, or more than 20 HPs/SSAs distributed throughout the colon.

Exclusion criteria

Exclusion criteria: Carriers of a germline mutation in the MutYH or APC gene and individuals who have undergone a total colonic resection.

Design outcomes

Primary

Measure	Time frame
To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.	—

Secondary

Measure	Time frame
The incidence of complications: The amount of polypectomies and the rate of protcol deviations and conversions to surgical resection will be assessed.	—

Contacts

Public ContactY. Hazewinkel

Meibergdreef 9

y.hazewinkel@amc.uva.nl+31 (0)20 5662806

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)