Pulmonary hypertension, pulmonary sarcoidosis
Conditions
Interventions
All patients will be screened for the presence of pulmonary hypertension by a standardized diagnostic strategy (Local standard protocol) including history taking and physical examination, electrocardi
Sponsors
St. Antonius Hospital
Eligibility
Inclusion criteria
Inclusion criteria: - Diagnosis of pulmonary sarcoidosis conforming the American Thoracic Society (ATS) criteria (confirmed by histology or cytology) or by consensus of a multidisciplinary ILD-team - Age 18 years or above
Exclusion criteria
Exclusion criteria: For 3D-echocardiography: - Pacemaker or Implantable Cardioverter Defibrillator (ICD) For IVUS and right heart catheterization: - Right heart mass (thrombus and/or tumor) - Patients with coagulopathy - Tricuspid or pulmonary valve mechanical prosthesis - Endocarditis of tricuspid or pulmonary valve - Frequent ventricular arrhythmias For IVUS only - Allergy to contrast - Glomerular Filtration Rate (GFR) <30 mL/min/1.73m2 as calculated by the Cockcroft-Gault Equation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Non-invasive diagnosis of pulmonary hypertension in pulmonary sarcoidosis. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Assessment of the etiology of pulmonary hypertension in pulmonary sarcoidosis in patients with pulmonary hypertension. 2. Development of pulmonary hypertension after 1 year follow up for patients who are initialy diagnosed as no pulmonary hypertension. | — |
Contacts
Public ContactMarloes P. Huitema
St Antonius Hospital Nieuwegein
Outcome results
None listed