Acute ischemic stroke
Conditions
Interventions
The intervention is the acquisition of CTP in all patients undergoing evaluation for EVT at all intervention centers in the Netherlands. Infarct core size, penumbra size, core-penumbra mismatch and in
Sponsors
Leading the Change (LtC); ZonMW
Eligibility
Inclusion criteria
Inclusion criteria: • A clinical diagnosis of acute ischemic stroke. • CT or MRI scan ruling out intracranial hemorrhage. • Extracranial carotid and intracranial arterial occlusion demonstrated with CTP and CTA, MRA or DSA. • Intracranial proximal arterial occlusion of the anterior circulation (intracranial carotid artery (ICA, ICA-T) or middle (M1/M2) or anterior (A1/A2) cerebral artery), demonstrated by CTA, MRA or DSA. • Endovascular treatment was initiated; defined as groin puncture. • Age of 18 or above. • A score of at least 2 on the NIH Stroke Scale. • Written informed consent.
Exclusion criteria
Exclusion criteria: • Pre-stroke disability which interferes with the assessment of functional outcome at 90 days, i.e. mRS >2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The distribution of outcomes on the modified Rankin scale (mRS) at three months. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Barthel Index • EQ5D5L • Adverse events | — |
Contacts
Public ContactAyla van Ahee
Amsterdam UMC
Outcome results
None listed