Disrupting the rhythm of depression using e-mental health.

Disrupting the rhythm of depression: Cost-effectiveness of an e-mental health self management intervention (E-Self CT) with automated tele-monitoring for recurrent depression.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26980

Enrollment

268

Registered

2010-09-10

Start date

2010-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive Disorder, E-mental health, Prevention, Relapse, Online Cognitive behavior therapy, Cognitive behavior therapy

Interventions

When participants are selected into the intervention group, after randomization, they will receive E-Self CT in addition to CAU, (for example care of a general practitioner, secondary care or no care

Eligibility

Inclusion criteria

Inclusion criteria: Participant with a recurrent MDD (DSM-IV-TR) who suffered through at least two previous depressive episodes in the past five years. These participants have to be in remission according to DSM-IV criteria for longer than eight weeks and no longer than two years, and have to have a current score of </10 on the Hamilton Rating Scale for Depression (HRSD). Participants also need to be able to be fluent in Dutch and have to have access to the internet.

Exclusion criteria

Exclusion criteria: 1. Current mania or hypomania or a history of bipolar illness; 2. Psychotic disorder (current and previous); 3. Alcohol or drug misuse; 4. A predominant anxiety disorder for which treatment is obtained.

Design outcomes

Primary

Measure	Time frame
Cumulative person-time based incidence of depression relapse/recurrence over 24 months using DSM-IV-TR criteria as assessed by the Structural Clinical Interview for DSM-IV Axis I Disorders (SCID) based on the DSM-IV-TR. Given the results of previous studies, differential response dependent on number of previous depressive episodes will be examined explicit.	—

Secondary

Measure	Time frame
1. Number of relapse/recurrence; 2. Severity: Symptom severity as measured with the Inventory of Depressive Symptomatology (IDS-R); 3. Economic evaluation: A. Balance between costs and health outcomes with the Quality Adjusted Life Years (QALY) measured with the EQ-5D; B. Cost data stemming from production losses due to absenteeism and working less efficiently while at work will be collected with the TIC-P. 4. Treatment outcome for participants with co-morbidity with concurrent somatic illnesses assessed by the Health Survey Inquiry and additional questions concerning somatic illnesses; 5. Examining differential predictors of treatment outcome; 6. Mediators.	—

Measure

Time frame

1. Number of relapse/recurrence; 2. Severity: Symptom severity as measured with the Inventory of Depressive Symptomatology (IDS-R); 3. Economic evaluation: A. Balance between costs and health outcomes with the Quality Adjusted Life Years (QALY) measured with the EQ-5D; B. Cost data stemming from production losses due to absenteeism and working less efficiently while at work will be collected with the TIC-P. 4. Treatment outcome for participants with co-morbidity with concurrent somatic illnesses assessed by the Health Survey Inquiry and additional questions concerning somatic illnesses; 5. Examining differential predictors of treatment outcome; 6. Mediators.

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Contacts

Public ContactGemma Kok

Grote Kruisstraat 2/1

g.d.kok@rug.nl+31 (0)50 3639880

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)