PC-study

Pessary or Cerclage to Prevent Preterm birth in women with short cervical length and a history preterm birth.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26958

Enrollment

440

Registered

2014-01-29

Start date

2014-03-01

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preterm birth history of preterm birth short cervical length

Interventions

Pessary Cerclage

Eligibility

Inclusion criteria

Inclusion criteria: 1) Singleton pregnancy 2) previous preterm birth < 34 weeks of gestation AND 3)cervical length < 25mm or less on transvaginal ultrasound before 24 weeks of GA OR Indication for primary cerclage before 16 weeks in current pregnancy based on obstetric history, according to local protocol

Exclusion criteria

Exclusion criteria: 1) Maternal age less than 18 years 2) Inability to give informed consent 3) Placenta praevia 4) Vasa praevia 5) Premature Prelabour Rupture of the Membranes (PPROM) 6) Cervical dilatation iY3cm 7) Cervical length 2mm 8) Identified major congenital abnormalities. 9) Women with clinical signs of chorioamnionitis or signs of intra uterine infection

Design outcomes

Primary

Measure	Time frame
Preterm birth < 32 weeks of gestation	—

Secondary

Measure	Time frame
Neonatal outcomes Maternal outcomes	—

Contacts

Public ContactB. Koullali

AMC

b.koullali@amc.uva.nl-

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Feb 6, 2026