Antimicrobial resistance, Intensive care
Conditions
Interventions
1.Contact Isolation Precautions for patients colonized or infected with a carbapenem non-susceptible Gram-negative bacterium (Pseudomonas aeruginosa, Klebsiella pneumoniae, or Acinetobacter baumannii)
4 times daily -->
2% solutions of chlorhexidine
4. Environmental cleaning
5. Antibiotic Stewardship
6. Multifaceted program to improve hand hygiene compliance (including education, feedba
Sponsors
1.Faculty of Medicine Universitas Indonesia / Dr Cipto Mangunkusumo Hospital Jakarta, Indonesia
2. Erasmus MC Rotterdam, The Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: All adult patients (age ≥18 years old) admitted to the intensive care unit of Dr Cipto Mangunkusumo Hospital in Jakarta, Indonesia.
Exclusion criteria
Exclusion criteria: Patients who are discharged within 48 hours from the intensive care unit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of patients who acquire carriage or infection with A. baumannii with reduced susceptibility to carbapenems, P. aeruginosa with reduced susceptibility to carbapenems, or K. pneumoniae with reduced susceptibility to carbapenems per 100 patient-days at risk in the ICU. An acquisition is defined as a screening culture (throat or rectum) or clinical culture with a first detection of either A. baumannii, P. aeruginosa, or K. pneumoniae, all with reduced susceptibility to a carbapenem, that was not yet present on admission or in the first 48 hours of admission. Thus, for each patient, a maximum of three new acquisition events may occur. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measures include quantity and quality of antibiotic usage, the in-ICU crude mortality rate, the hand hygiene compliance of health care workers, and environmental contamination of the above mentioned Gram-negative bacteria with reduced susceptibility to carbapanems. | — |
Contacts
Public ContactJuliette Severin
Erasmus MC
Outcome results
None listed