1. Throat infections
Conditions
Interventions
Adenotonsillectomy within 6 weeks versus watchful waiting. During the study, the child's temperature was measured daily with a validated infrared tympanic membrane thermometer with an electronic devic
i.e. sore throat, pain/difficulty at swallowing, cough, rhinorrhea, earache and otorrhea. They also noted absence from day-care or school due to upper respiratory infections, and resource use such as
Sponsors
University Medical Center Utrecht
PO box 85500
3508 GA Utrecht
The Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 2 to 8 years indicated for adenotonsillectomy according to current medical practice. These included children with recurrent throat infections (3 or more episodes per year) or other indications such as obstructive complaints or recurrent upper respiratory infections.
Exclusion criteria
Exclusion criteria: Children with: 1. A history of 7 or more throat infections in the preceding year, or 5 or more in each of the two preceding years, or 3 or more in each of the 3 preceding years (Paradise criteria); 2. High suspicion of obstructive sleep apnoea, i.e. Brouillette¡¦s OSA-score of more than 3.5; 3. Down¡¦s syndrome; 4. Craniofacial malformation, such as cleft palate; 5. Documented immunodeficiency, other than IgA or IgG2 deficiencies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of fever episodes defined as a body-temperature of 38.0 C or higher for at least one day. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures were: 1. Throat infections; 2. Sore throat days and episodes; 3. Upper respiratory infections; 4. Otitis media; 5. Sleeping and eating pattern; 6. Length and weight; 7. Absence from day-care or school due to upper respiratory infections; 8. Health-related quality of life; 9. Costs; 10. Immunological parameters; 11. Oropharyngeal microbial flora. | — |
Contacts
Public ContactAnne G.M. Schilder
University Medical Center Utrecht Wilhelmina Children's Hospital Department of Otorhinolaryngology PO Box 85090
Outcome results
None listed