diabetes suikerziekte
Conditions
Interventions
Drinking nutridrink or water while a FMRI is being made.
Sponsors
Prof. dr. H. Pijl
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy males; 2. Age 19-29; 3. BMI 19-25 kg/m2; 4. Stable weight for the last 2 years; 5. Caucasian; 6. No family history of DM2.
Exclusion criteria
Exclusion criteria: 1. Use of medication known to affect glucose metabolism (for example prednison) or lipid metabolism; 2. History of genetic or psychiatric disease (e.g. fragile X syndrome, major depression) that affects the brain; 3. Significant chronic disease; 4. Galactosemia; 5. Renal or hepatic disease; 6. Recent weight changes or attempts to lose or gain weight (> 3 kg weight gain or loss, within the last 3 months); 7. Smoking (current); 8. Alcohol consumption of more than 28 units per week at present or in the past; 9. Recent blood donation (within the last 3 months); 10. Contra-indication to MRI scanning: A. Claustrophobia; B. Pacemakers and defibrillators; C. Nerve stimulators; D. Intracranial clips; E. Intraorbital or intraocular metallic fragments; F. Cochlear implants; E. Ferromagnetic implants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypothalamic neuronal activity as measured with FMRI. | — |
Contacts
Public ContactM.A. Wijngaarden
Outcome results
None listed