Laryngeal stenosis
Conditions
Interventions
Health- and voice related questionnaires, MRI, spirometry, vocal test
Sponsors
Erasmus MC- Sophia Children's Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Undergone surgical reconstruction for a congenital or acquired laryngeal stenosis between 1994 and 2011 (minimum 6 years of age), informed consent by parents and/or patient
Exclusion criteria
Exclusion criteria: Contra- indications for MRI, inability to undergo MRI, any current lung infection (symptoms of respiratory distress, severe cough, antibiotics for current lung infection), chronic oxygen need, tracheotomy cannula in situ
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes of this study are the findings on MRI. In the first sub study we will classify post-surgical changes. In the second sub study we will quantify the extent and location of fibrosis. Lastly, in the third sub study, we will quantify the mobility of the vocal cords. | — |
Secondary
| Measure | Time frame |
|---|---|
| The MRI findings from the first and second sub study will be correlated to clinical status. Clinical status will be assessed through patient history, health related questionnaires, physical examination and spirometry. Findings from the third sub study will be correlated to the rate of dysphonia assessed by the Dysphonia Severity Index and voice questionnaires. | — |
Contacts
Public ContactH.A.W.M. Tiddens
Erasmus Medical Center, Sophia Children’s Hospital Rotterdam, Department of Pediatric Pulmonology, Dr. Molewaterplein 60
Outcome results
None listed