All systemic autoimmune diseases
Conditions
Interventions
None listed
Sponsors
Reade Research BV
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Age = 18 years. For patients: - Diagnosed by their treating physician with a systemic autoimmune disease. For controls: - Belonging to family or close friend of patient (of the same gender).
Exclusion criteria
Exclusion criteria: Patients who meet the following criteria will be excluded from the study: - Language problems precluding the completion of the questionnaire; - Likelihood of absence in the next 6 months; - Lack of informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our primary study parameter is the percentage of participants with a positive IgM or IgG response admitted to the hospital. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other parameters include: - The percentage of participants with a positive IgM or IgG response admitted to the ICU, and mortality due to SARS-CoV-2; - The geometric mean antibody titre over time; - The geometric mean and incidence of different antibody profiles (IgM/G/A, IgG1/3) and repertoire (anti-SP, anti-NP); - The geometric mean antibody avidity; - The percentage of patients who changed the dosage or use of their DMARD; - Mean rheumatic disease activity. | — |
Contacts
Public ContactFemke Hooijberg
Reade, Jan van Breemen Research Institute
Outcome results
None listed