Surgeries related to dDuodenal-jejunal-ileal atresia repairs, anorectal malformation, Hirschsprung disease and/or inguinal hernia
Conditions
Interventions
None listed
Sponsors
Emma Children’s Hospital, Amsterdam UMC.
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: age 12 months (± four weeks) with a history of general anesthesia exposure (patient group) or without a history of general anesthesia (healthy controls)
Exclusion criteria
Exclusion criteria: Children with comorbid conditions affecting structure and/or function of the central nervous system (e.g. premature birth) will be excluded from participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurocognitive development as measured using eye-tracking metrics | — |
Secondary
| Measure | Time frame |
|---|---|
| a. Conventional measures of neurocognitive development (Ages & Stages Questionnaire and Bayley Scales of Infant Development ) b. Total anesthesia time. Surgery and anesthesia time will be recorded by the (fellow) surgeon performing the operation(s). When multiple procedures are carried out, durations will be combined and these results will be retrieved during analysis of the data. | — |
Contacts
Public ContactSanne Maat
Amsterdam UMC
Outcome results
None listed