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Dual energy CT for comprehensive cardiac imaging in patients suspected of coronary artery disease

Dual energy CT for comprehensive cardiac imaging in patients suspected of coronary artery disease

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
NL-OMON
Registry ID
NL-OMON26825
Enrollment
50
Registered
2016-02-11
Start date
2016-03-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease/ coronaire hartziekte Dual energy CT Perfusion imaging/ Perfusie beeldvorming

Interventions

Dual energy CT scan and CT angiography

Sponsors

University Medical Center Groningen
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Stable angina pectoris • Nuclear MPI within the last 60 days • Scheduled for ICA • Patients must provide consent in writing after proper education and discussion with the treating physician and/or research physician • 50 years or older

Exclusion criteria

Exclusion criteria: • Cardiac rhythm other than sinus • Second or third degree atrioventricular block • Prolonged QT-time • Sick-sinus syndrome • Asthma or chronic obstructive pulmonary disease • Contraindications for iodine contrast • Thyroid gland disorders • Renal insufficiency (eGFR 65 bpm and contraindications for beta-blocker • Severe arterial hypertension (>220/120 mmHg) • Severe arterial hypotension (35) • Severe physical deterioration due to concomitant illness • Language barrier • Acute coronary syndrome • Pregnancy • Claustrophobia • Using of persantin, theophylline, digoxin or verapamil, if temporarily stopping (48h) is not possible • Contraindications for CTA: presence of pacemaker or ICD leads, AF, pregnancy, BMI >35 kg/m2, prosthetic heart valve • Previously documented myocardial infarction/PCI/CABG

Design outcomes

Primary

MeasureTime frame
The diagnostic accuracy of the rest coronary CT angiography in combination with stress dual energy CT in comparison to SPECT and invasive coronary angiography in patients with a intermediate to high risk of coronary artery disease.—

Secondary

MeasureTime frame
Diagnostic accuracy of myocardial ischemia detection using DECT in comparison to SPECT ischemia detection in patients with a intermediate to high risk of coronary artery disease, radiation dose.—

Contacts

Public ContactR. Vliegenthart

Center for Medical Imaging - North East Netherlands Dept of Radiology University of Groningen / University Medical Center Groningen

r.vliegenthart@umcg.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)