Chronic ventilatory support
Conditions
Interventions
The proposed intervention to be studied is initiation of HMV at home as compared to in hospital initiation I different settings. Recently a pilot study was performed in Groningen in which the initiati
Sponsors
Universital Medical Center Groningen
Maastricht Universital Medical Center
Universital Medical Center Utrecht
Erasmus Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: Indication to initiate non-invasive ventilatory support in patients with a neuromuscular disease or thoracic cage abnormality who suffer from complaints of alveolar hypoventilation (fatigue, headache of dyspnoea) combined with all following elements: - arterial carbon dioxide > 6.0 kPa daytime or arterial or transcutaneous carbon dioxide > 6.0 kPa at night or orthopnea as a result of diaphragm paralysis - Age > 18 years - Existence, of a sufficient network (social or professional) according to the supervising HMV center making initiation of HMV at home possible and safe.
Exclusion criteria
Exclusion criteria: - Patients who already have had HMV due to acute respiratory failure - Necessity for invasive ventilatory support - Patients admitted to a nursing home
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary objective: - Daytime arterial carbon dioxide (PaCO2) assessed without oxygen supplementation and ventilatory support while the patient is in sitting position | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objective: - Health related quality of life - Lung function - Nocturnal transcutaneous carbon dioxide and saturation - Costs | — |
Contacts
Public ContactAnda Hazenberg
Universitair Medisch Centrum Groningen Centrum voor Thuisbeademing
Outcome results
None listed