Common (not genital) warts
Conditions
Interventions
Treatment arms
For the treatment with cryotherapy we chose for a high-intensity regimen: a 2-weekly consultation till the
wart has disappeared (until max. 13 weeks), 3 applications of the same wart pe
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: All patients from the age of 4 onward, who present themselves to their practice with one or more new warts of the type vulgaris on hands or feet will be included? New warts are warts who are presented for the first time in the general practice by patients who have had no general practice (or dermatological) treatment for warts in the past year. For all patients duration of presence of the warts and the previous treatment(s) will be registered.
Exclusion criteria
Exclusion criteria: Exclusion criteria are: immuno-incompetent patients and mosaic warts larger than 1 cm in diameter.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is defined as ‘cure', which means that the wart(s) have totally disappeared (normal skin) at 13 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The number of warts that still exists at follow-up, irrespective of the extent of regression (because for a separate wart regression can not be validly assessed.); 2. The subjective hindrance caused by the warts as scored by the patient on a numerical rating scale (0-10); 3. The subjective hindrance caused by the treatment as scored by the patient on a seven point scale (during the treatment period this will be scored weekly in a booklet); 4. Pain and other adverse effects of the treatments (pain, new warts, scars, irritation of the skin, dermatitis discomfort, invalidation, time); 5. Subjective judgement of the effect of the treatment by the patient at follow-up subjective judgement of the effect of the treatment by the research nurse at follow-up; 6. Referral to a dermatological department , assessed at 26 weeks After three months of the intervention period, patients for whom the warts have not disappeared are free to Switch therapy. In the follow-up period we will carefully register to which therapies patients have switched and also if, and after how long this therapy leads to total disappearance of the warts; 7. The consumption of co-interventions during the intervention period and thereafter will also be used as secondary endpoints. | — |
Contacts
Public ContactJ.A.H. Eekhof
Leiden University Medical Center (LUMC), P.O. Box 2088
Outcome results
None listed